Discovery of Small-Molecule Modulators of Protein-RNA Interactions for Treating Cancer and COVID-19
by Wan Gi Byun
English | 2022 | ISBN: 9811978131 | 156 pages | True PDF,EPUB | 41.14 MB

This book describes the development of novel protein-RNA-binding assays and their applications in a high-throughput manner for the identification of small-molecule modulators of protein-RNA interactions to treat cancer and COVID-19.

Modulating protein-RNA interactions with small molecules is expected to provide novel biological insights of the interrelation of diseases with the protein-RNA interactome. The modulations may also be exploited therapeutically. For these reasons, the development of a simple, reliable, and sensitive protein-RNA-binding assay is necessary for high-throughput screening to discover new effective chemical entities capable of acting on diverse protein-RNA interactions. This book discusses the discovery of small-molecule modulators targeting protein-RNA interactions that are potentially valuable to treat cancer and COVID-19 by constructing novel high-throughput screening methods. The results of this dissertation provide valuable insights into the regulation of protein-RNA interactions in chemical biology and drug development.

Code:
https://k2s.cc/file/bab1360719312/Discovery_of_Small-Molecule_Modulators_of_Protein%D0%91%E2%94%80%E2%8C%A0RNA_Interactions_for_Treating_Cancer_and_COVID-19.rar
Code:
https://rapidgator.net/file/73a1d63acb34a0a9eca61d89e217fcdd/Discovery_of_Small-Molecule_Modulators_of_Protein-RNA_Interactions_for_Treating_Cancer_and_COVID-19.rar.html